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Paul J R Barton Selected Research

Clenbuterol

12/2010Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1.
6/2009Chronic treatment with clenbuterol modulates endothelial progenitor cells and circulating factors in a murine model of cardiomyopathy.
6/2009A gene expression profile of the myocardial response to clenbuterol.
3/2008Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure.
8/2005Myocardial insulin-like growth factor-I gene expression during recovery from heart failure after combined left ventricular assist device and clenbuterol therapy.

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Paul J R Barton Research Topics

Disease

22Heart Failure
01/2015 - 07/2003
7Cardiomyopathies (Cardiomyopathy)
01/2019 - 08/2005
6Hypertrophy
10/2015 - 11/2002
6Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2015 - 12/2006
6Cardiomegaly (Heart Hypertrophy)
10/2011 - 11/2002
4Heart Diseases (Heart Disease)
04/2014 - 07/2009
3Fibrosis (Cirrhosis)
01/2022 - 01/2019
2Neoplasms (Cancer)
01/2019 - 09/2011
2Myocardial Infarction
01/2019 - 06/2011
1Myocardial Ischemia (Ischemic Heart Diseases)
04/2014
1Mitochondrial Diseases (Mitochondrial Disease)
10/2011
1Cicatrix (Scar)
06/2011
1Cardiac Arrhythmias (Arrythmia)
07/2009
1Infarction (Infarctions)
08/2008
1Ventricular Tachycardia
05/2007
1Atrophy
08/2005
1Hypertension (High Blood Pressure)
09/2004
1Inflammation (Inflammations)
09/2004
1Shock
11/2002

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
01/2019 - 09/2011
6Messenger RNA (mRNA)IBA
09/2011 - 11/2002
5ClenbuterolIBA
12/2010 - 08/2005
4ConnectinIBA
01/2019 - 02/2012
3Transcription Factors (Transcription Factor)IBA
10/2015 - 11/2002
3CytokinesIBA
06/2011 - 02/2004
2RNA-Binding Proteins (RNA-Binding Protein)IBA
10/2019 - 08/2014
2cysteine and glycine-rich protein 3IBA
10/2015 - 06/2009
2CalcineurinIBA
10/2015 - 06/2011
2Insulin-Like Growth Factor I (IGF-1)IBA
12/2010 - 08/2005
2Matrix Metalloproteinases (MMPs)IBA
12/2006 - 07/2003
1CreatinineIBA
01/2022
1Pharmaceutical PreparationsIBA
01/2019
1Cytoskeletal ProteinsIBA
10/2015
1AMP Deaminase (Myoadenylate Deaminase)IBA
04/2014
1NucleotidesIBA
04/2014
1endonuclease GIBA
10/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2011
1CalciumIBA
06/2011
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
06/2011
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2011
1LDL CholesterolIBA
06/2011
1IntegrinsIBA
06/2009
1erucylphosphocholineIBA
06/2009
1Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
06/2009
1FollistatinIBA
11/2008
1UbiquitinIBA
08/2008
1Proteasome Endopeptidase Complex (Proteasome)IBA
08/2008
1Phosphates (Orthophosphate)IBA
05/2007
1Metalloproteases (Metalloproteinases)IBA
12/2006
1CollagenIBA
12/2006
1Collagenases (Collagenase)FDA Link
12/2006
1EnzymesIBA
07/2006
1CreatineIBA
07/2006
1glycine amidinotransferase (arginine-glycine amidinotransferase)IBA
07/2006
1Glucose (Dextrose)FDA LinkGeneric
04/2005
1Interleukin-1beta (Interleukin 1 beta)IBA
09/2004
1SpectrinIBA
07/2003
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
11/2002
1Sorbitol (Yal)FDA Link
11/2002
1Endothelin-1 (Endothelin 1)IBA
11/2002

Therapy/Procedure

11Heart-Assist Devices
02/2011 - 07/2003
8Therapeutics
01/2019 - 07/2003
8Transplantation
06/2011 - 09/2004
4Heart Transplantation (Grafting, Heart)
02/2011 - 07/2003
1Drug Therapy (Chemotherapy)
01/2019
1Lung Transplantation
09/2004
1Cell Transplantation
09/2004